Under detection and underreporting are problematic for a variety of reasons. They make it more difficult to understand the true spread of the virus, which impacts everything from resource planning in healthcare systems to public policies designed to reduce infection spread.
Over the past decade, bloodstream infections (BSI) caused by nontyphoidal Salmonella have killed approximately 650,000 people globally. Salmonella is also the most frequently isolated pathogen in hospitalized patients diagnosed with community-onset BSI in Africa and Asia.
Releasing a vaccine to the public where it can make a positive impact on public health and individual lives is a complex process. Quality control testing is critical at every stage, from initial development to full-scale production, to make sure vaccines are as safe as possible.