Sepsis is the body’s life-threatening, imbalanced response to a severe infection. The condition affects 1.7 million people and takes 270,000 lives in the U.S. every year. This year, we face additional risks because of the threat of COVID-19.
As cases of COVID-19 are on the rise again in several places in the U.S., the need for effective treatment remains. Many potential COVID-19 treatments that could have an impact on our ability to fight the virus are currently being developed or tested in clinical trials.
The Global Sepsis Alliance has stated that COVID-19 can cause sepsis, the body’s overwhelming and life-threatening response to an infection that can lead to organ damage and death. In the U.S., one in three patients who die in a hospital die of sepsis. Many different types of infections can cause sepsis, but the most common cause is pneumonia.
Hospitalizations with acute kidney injury (AKI) more than quadrupled in the US from 2000-2014 and clinicians are increasingly recognizing AKI as an in-hospital complication of sepsis, heart conditions, and surgery.