Clinical presentation of kidney involvement from COVID-19 can range from mild proteinuria to progressive AKI, requiring renal replacement therapy (RRT).
COVID-19 is not just any respiratory virus. Researchers have quickly discovered that it is capable of directly affecting multiple organ systems, and that it can also cause a host of related complications. Among those complications are endothelial dysfunction, sepsis, and acute kidney injury.
It is especially important to focus on prevention methods amid the COVID-19 pandemic—in previous reports of SARS and MERS-CoV infections, AKI developed in 5% to 15% of cases and carried an extremely high (60%-90%) mortality rate.
Hospitalizations with acute kidney injury (AKI) more than quadrupled in the US from 2000-2014 and clinicians are increasingly recognizing AKI as an in-hospital complication of sepsis, heart conditions, and surgery.